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Carcinogenic Activity of Some Fluorinated Polycyclics

Abstract

CARCINOGENIC hydrocarbons, substituted by fluorine especially in the K-region, have been synthesized recently in a number of laboratories. As fluorine substitution alters the geometrical form of the parent molecule only very little, while it can be expected to have a marked effect on the electron density1, its effect on the carcino-genicity of the parent compound may well help in further elaboration of the theories existing in this field.

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References

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BERGMANN, E., BLUM, J. & HADDOW, A. Carcinogenic Activity of Some Fluorinated Polycyclics. Nature 200, 480 (1963). https://doi.org/10.1038/200480a0

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