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Agglutinability of Red Cells by Anti-i in Patients with Thalassæmia Major and Other Hæmatological Disorders

Abstract

SEVERAL blood group antigens are more strongly reactive on adult red cells than on the red cells of new-born infants. A notable exception is the antigen i, which is maximally developed at birth and decreases in strength during the first year of life1. The decrease in antigen i is associated with a reciprocal increase in antigen I, which is poorly developed at birth.

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References

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GIBLETT, E., CROOKSTON, M. Agglutinability of Red Cells by Anti-i in Patients with Thalassæmia Major and Other Hæmatological Disorders. Nature 201, 1138–1139 (1964). https://doi.org/10.1038/2011138a0

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