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Sedimentation Behaviour and Molecular Weight of Choline Acetyltransferase

Abstract

THE human placenta is known to be a rich source of choline acetyltransferase (acetyl CoA: choline-o-acetyltransferase E.C. 2.3.1.6)1. Investigations have shown that this enzyme is very similar, in its kinetic behaviour and specificity, to choline acetyltransferase from other sources. In the foregoing work and in the course of purification of the placental enzyme (Morris, D., unpublished) it was of interest to determine its molecular weight, and to compare its sedimentation characteristics with that of rabbit brain enzyme.

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BULL, G., FEINSTEIN, A. & MORRIS, D. Sedimentation Behaviour and Molecular Weight of Choline Acetyltransferase. Nature 201, 1326 (1964). https://doi.org/10.1038/2011326a0

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