Abstract
IT has been previously demonstrated, that dl-nor-epinephrine-3H is bound by the isolated perfused dog gracilis muscle and that nerve stimulation causes a release of the bound nore-epinephrine-3H. Both nor-epinephrine-3H and epinephrine-3H are bound in dense core vesicles of sympathetic nerve endings1. We therefore examined the possibility that epinephrine-3H taken up from the circulation could also be released by stimulation of sympathetic nerves.
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References
Wolfe, D. E., and Potter, L. T., Anat. Rec., 145, 301 (1963).
Rosell, S., Kopin, I. J., and Axelrod, J., Amer. J. Physiol., 205, 317 (1963).
Kopin, I. J., Axelrod, J., and Gordon, E., J. Biol. Chem., 236, 2109 (1961).
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ROSELL, S., AXELROD, J. & KOPIN, I. Release of Tritiated Epinephrine following Sympathetic Nerve Stimulation. Nature 201, 301 (1964). https://doi.org/10.1038/201301a0
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DOI: https://doi.org/10.1038/201301a0
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