Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Letter
  • Published:

Carcinogenic Activity of Aflatoxin to Rats

Abstract

THE observations1,2 that toxic groundnut meal when fed to rats will lead to the development of liver cancer have been amply confirmed3–5. It remained necessary, however, to demonstrate that the mould product, aflatoxin, which is responsible for the acute toxic effects of contaminated meals6 is also responsible for the carcinogenic activity.

This is a preview of subscription content, access via your institution

Access options

Buy this article

USD 39.95

Prices may be subject to local taxes which are calculated during checkout

Similar content being viewed by others

References

  1. Schoental, R., Brit. J. Cancer, 15, 812 (1961).

    Article  CAS  Google Scholar 

  2. Lancaster, M. L., Jenkins, F. P., and Philp, J. McL., Nature, 192, 1095 (1961).

    Article  ADS  Google Scholar 

  3. Salmon, W. D., and Newbarnes, M., Cancer Res., 23, 511 (1963).

    Google Scholar 

  4. Le Breton, E., Frayssinet, C., and Boy, J., C.R. Acad. Sci., Paris., 255, 784 (1962).

    Google Scholar 

  5. Butler, W. H., and Barnes, J. M., Brit. J. Cancer., 17, 699 (1963).

    Article  CAS  Google Scholar 

  6. Allcroft, R., and Carnaghan, R. B. A., Chem. and Indust., (2), 50 (1963).

  7. Spensley, P. C. (personal communication).

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

BARNES, J., BUTLER, W. Carcinogenic Activity of Aflatoxin to Rats. Nature 202, 1016 (1964). https://doi.org/10.1038/2021016a0

Download citation

  • Issue date:

  • DOI: https://doi.org/10.1038/2021016a0

This article is cited by

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing