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Oxidation of Glutathione and Other Thiols by the Xanthine Oxidase and Hypoxanthine of Rat Liver Homogenates

Abstract

GLUTATHIONE (GSH) is rapidly oxidized to GSSG when incubated in a rat liver homogenate. The reaction is enzymatic since it is largely prevented by previously heating the homogenate1,2. The following observations have now been made (Table 1).

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References

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JOCELYN, P. Oxidation of Glutathione and Other Thiols by the Xanthine Oxidase and Hypoxanthine of Rat Liver Homogenates. Nature 202, 1115 (1964). https://doi.org/10.1038/2021115a0

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