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Hydrocortisone and the Apparent Induction Period for Antibody Formation in vitro
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  • Letter
  • Published: 16 May 1964

Hydrocortisone and the Apparent Induction Period for Antibody Formation in vitro

  • W. J. HALLIDAY1 nAff2 &
  • JUSTINE S. GARVEY1 

Nature volume 202, page 712 (1964)Cite this article

  • 407 Accesses

  • 3 Citations

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Abstract

SEVERAL investigations1–4 into the production of antibodies by lymphoid tissue in vitro have shown that, following antigenic stimulation in vivo, the tissue (lymph node or spleen) must remain in the animal for several days before it can be removed to give antibody-producing cultures. A requirement for such an ‘induction period’ has been demonstrated for both primary and secondary responses.

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References

  1. Stavitsky, A. B., Adv. Immunol., 1, 225 (1961).

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  2. Stavitsky, A. B., and Wolf, B., Biochim. Biophys. Acta, 27, 4 (1958).

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  3. Cremer, N. E., J. Immunol., 90, 685 (1963).

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  4. Kong, Y. M., and Johnson, A. G., J. Immunol., 90, 672 (1963).

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  5. Ambrose, C. T., N.C.I. Monog., 11, 117 (1963); Fed. Proc., 22, 266 (1963).

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  6. Stavitsky, A. B., J. Immunol., 72, 360 (1954).

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Author information

Author notes
  1. W. J. HALLIDAY

    Present address: Department of Microbiology, University of Queensland, Brisbane

Authors and Affiliations

  1. Laboratory of Immunochemistry, California Institute of Technology, Pasadena

    W. J. HALLIDAY & JUSTINE S. GARVEY

Authors
  1. W. J. HALLIDAY
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  2. JUSTINE S. GARVEY
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Cite this article

HALLIDAY, W., GARVEY, J. Hydrocortisone and the Apparent Induction Period for Antibody Formation in vitro. Nature 202, 712 (1964). https://doi.org/10.1038/202712a0

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  • Issue date: 16 May 1964

  • DOI: https://doi.org/10.1038/202712a0

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This article is cited by

  • Cortisol and the Immune Response

    • GAIL L. SOREM
    • GERONIMO TERRES

    Nature (1966)

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