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New Motor End-plates and their Relationship to Muscle Fibre Injury

Abstract

IT has been shown by Guth and Zalewski1, Hofmann et al.2, Koenig3 and Miledi4 that new motor end-plates will form in denervated skeletal muscle or muscle devoid of its original motor end-plates in mammals and amphibians following implantation of a motor nerve. However, in all these experiments the muscle suffered considerable damage, either during implantation of the nerve or in transecting the muscle to remove the original motor end-plate zone.

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References

  1. Guth, L., and Zalewski, A., Exp. Neurol., 7, 316 (1963).

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  2. Hofmann, W. W., Thesleff, S., and Zelena, J., J. Physiol., 171, 27 P (1964).

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  3. Koenig, J., C.R. Acad. Sci. Paris, 256, 2918 (1963).

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  4. Miledi, R., Nature, 199, 1191 (1963).

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GWYN, D., AITKEN, J. New Motor End-plates and their Relationship to Muscle Fibre Injury. Nature 203, 651–652 (1964). https://doi.org/10.1038/203651a0

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  • DOI: https://doi.org/10.1038/203651a0

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