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Sub-cellular Localization of Rat Kidney Alkaline Phosphatase

Nature volume 204, pages 476–478 (1964)Cite this article

Abstract

IN mammalian cell cultures alkaline phosphatase is regulated by both inductive and repressive mechanisms1. In preparation for further investigations of the mechanisms of alkaline phosphatase control, the sub-cellular localization of this enzyme was re-investigated, using newer techniques2,3. Previous investigations, using the kidney and intestine of several different mammalian species, have shown that the highest alkaline phosphatase activity resides on the microsomes4-6.

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References

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Author information

Author notes

  1. MARTIN J. GRIFFIN: Genetics trainee.

  2. RODY P. COX: Career Scientist, Health Research Council of the City of New York.

Authors and Affiliations

  1. Department of Medicine, New York University School of Medicine, New York, 16, N.Y.

    MARTIN J. GRIFFIN & RODY P. COX

  2. The Summer Institute, Will Rogers Hospital and O'Donnell Memorial Research Laboratories, Saranac Lake, New York

    MARTIN J. GRIFFIN & RODY P. COX

Authors
  1. MARTIN J. GRIFFIN
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  2. RODY P. COX
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GRIFFIN, M., COX, R. Sub-cellular Localization of Rat Kidney Alkaline Phosphatase. Nature 204, 476–478 (1964). https://doi.org/10.1038/204476a0

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