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Further Simplification of the Purification Procedure of Influenza Virus on Barium Sulphate

Nature volume 205, page 828 (1965)Cite this article

Abstract

A METHOD for the purification of influenza virus by adsorption to and elution from BaSO4 with subsequent ultracentrifugation of the eluate has been published by Mizutani1. We have found that this method can be further simplified by separation of the citrate (necessary for elution but interfering with adsorption) in the form of its calcium salt after elution from BaSO4 has been achieved. By this step the ultracentrifugation of the eluate is eliminated and repeated purification cycles on the BaSO4 can be performed.

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References

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Authors and Affiliations

  1. Department of Biochemistry and Isotope Research, State Institute of Hygiene, Budapest, IX

    M. KLEMBALA & I. SZÉKÁCS

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  1. M. KLEMBALA
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  2. I. SZÉKÁCS
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KLEMBALA, M., SZÉKÁCS, I. Further Simplification of the Purification Procedure of Influenza Virus on Barium Sulphate. Nature 205, 828 (1965). https://doi.org/10.1038/205828a0

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