Abstract
A NUMBER of reports have recently been published dealing with the electrophoretic properties of water-soluble lens proteins of albino rats and the presence of a ‘fast’ anodic fraction in electrophoretic patterns of lens proteins from galactose- and lactose-fed rats1,2. It is well established that dense cataractous opacities develop in rat lenses within two to three weeks of galactose feeding3. Electrophoretic analysis of such lens extracts shows that the fraction with the highest anodic mobility is considerably increased when compared to normal rat lens4. There is, furthermore, an overall decrease in fractions migrating toward the cathode.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on SpringerLink
- Instant access to the full article PDF.
USD 39.95
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Korc, I., and Calcagno, M., Nature, 203, 691 (1964).
Wittgenstein, E., and Rowe, K. W., jun., Fed. Proc., 22, 478 (1963).
Mitchell, H. S., Proc. Soc. Exp. Biol. and Med., 32, 971 (1935).
Wittgenstein, E., and Rowe, K. W., jun., Investig. Ophth., 2, 285 (1963).
Grabar, P., and Williams, C. A., Biochim. Biophys. Acta, 10, 193 (1953).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
WITTGENSTEIN, E., ROWE, K. Agar-gel Electrophoresis of Soluble Lens Proteins in Galactose-fed Rats. Nature 208, 386–387 (1965). https://doi.org/10.1038/208386b0
Issue date:
DOI: https://doi.org/10.1038/208386b0
