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Sex-associated Protein in Liver Tissue of the Rat

Abstract

A PROTEIN component has been described1–3 which appeared to be present in liver tissue of the male rat but absent from that of the female. The response of this substance to varied endocrine manipulation suggests that its presence or absence is dependent on the sex hormones, testosterone potentiating and oestradiol inhibiting the formation, of the protein. Recently4, this work has been confirmed and extended to show that progesterone also has an effect causing the appearance of the protein in the female and an increase in the amount found in the castrated male.

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References

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BOND, H. Sex-associated Protein in Liver Tissue of the Rat. Nature 209, 1026 (1966). https://doi.org/10.1038/2091026a0

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