Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Letter
  • Published:

Release of Ganglioside from Guinea-pig Lung Tissue during Anaphylaxis

Nature volume 209, pages 1251–1252 (1966)Cite this article

Abstract

RECENTLY the chemical structures of the gangliosides have been elucidated1. Besides their occurrence in brain, Svennerholm has isolated a ganglioside (believed to be N-acetylneuraminic acid (2–3) galactosyl-β-(1–4) glucosyl acyl sphingosine) from human spleen2 and human lung3. A similar substance has been isolated from guinea-pig lung in this laboratory, and also from crude extracts of the slow-reacting substance of anaphylaxis.

This is a preview of subscription content, access via your institution

Access options

Buy this article

  • Purchase on SpringerLink
  • Instant access to the full article PDF.

USD 39.95

Prices may be subject to local taxes which are calculated during checkout

Similar content being viewed by others

References

  1. Svennerholm, L., J. Lipid Res., 5, 145 (1963).

    Google Scholar 

  2. Svennerholm, L., Acta Chem. Scand., 17, 860 (1963).

    Article  CAS  Google Scholar 

  3. Svennerholm, L. (personal communication) (1964).

  4. Svennerholm, L., Nature, 177, 524 (1956).

    Article  ADS  CAS  PubMed  Google Scholar 

  5. Svennerholm, E., and Svennerholm, L., Acta Chem. Scand., 16, 1282 (1962).

    Article  CAS  Google Scholar 

  6. Warren, L., J. Biol. Chem., 234, 1961 (1959).

    Google Scholar 

  7. Hodge, J. E., and Hofreiter, B. T., in Methods of Carbohydrate Chemistry, edit. by Whisler, R. L., and Wolfram, M. L., 1, 388 (Academic Press, London and New York, 1962).

    Google Scholar 

  8. Rondle, C. J. M., and Morgan, W. T. J., Biochem. J., 61, 586 (1955).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  9. Barlett, G. R., J. Biol. Chem., 234, 466 (1959).

    Google Scholar 

  10. Brocklehurst, W. E., J. Physiol., 151, 416 (1960).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  11. Svennerholm, L., J. Neurochem., 10, 613 (1963).

    Article  CAS  PubMed  Google Scholar 

  12. Anderson, D. M., Goadby, P., and Smith, W. G., Intern. Arch. Allergy, 22, 131 (1963).

    Article  CAS  Google Scholar 

  13. Brocklehurst, W. E., Prog. Allergy, 6, 539 (1962).

    CAS  PubMed  Google Scholar 

  14. Ängäard, E., Serqvist, J., Högberg, B., Johannson, K., Thon, I. L., and Uvnäs, B., Acta Physiol. Scand., 59, 97 (1963).

    Article  Google Scholar 

  15. Smith, W. G., Life Sci., 1, 133 (1962).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Research Laboratory in Biochemical Pharmacology, School of Pharmacy, Sunderland

    W. G. SMITH

Authors
  1. W. G. SMITH
    View author publications

    Search author on:PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

SMITH, W. Release of Ganglioside from Guinea-pig Lung Tissue during Anaphylaxis. Nature 209, 1251–1252 (1966). https://doi.org/10.1038/2091251a0

Download citation

  • Issue date:

  • DOI: https://doi.org/10.1038/2091251a0

This article is cited by

Search

Advanced search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing