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Particles in Leucocytes of Normal Humans Beings after Negative Staining in Electron Microscopy

Abstract

THE negative staining technique for the study of cells and cellular components by electron microscopy has been described by Almeida and Howatson1. A similar method has been applied to study the morphology of the Moloney leukaemia virus in megakaryocytes in experimentally infected mice2. Recently, virus-like particles have been described in the plasma of many leukaemic humans examined by a negative-staining technique3–6. This report describes the application of a similar technique to leucocytes of normal human beings.

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References

  1. Almeida, J. D., and Howatson, A. F., Proc. Fifth Intern. Congr. Electron Micros. 1962, 2, (abst. MM4) (Academic Press, New York, 1962).

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  3. Smith, K. O., Benyesh-Melnich, M., and Fernbach, D. J., J. Nat. Cancer Inst., 33, 557 (1964).

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DOLOWY, W., CORNET, J. & HENSON, D. Particles in Leucocytes of Normal Humans Beings after Negative Staining in Electron Microscopy. Nature 209, 1358–1359 (1966). https://doi.org/10.1038/2091358a0

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