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Role of the Amino-Acid ‘Code’ and of Selection for Conformation in the Evolution of Proteins

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References

  1. Epstein, C. J., Nature, 203, 1350 (1964).

    Article  ADS  CAS  Google Scholar 

  2. Anfinsen, C. B., Brookhaven Symp. Biol., 15, 194 (1962).

    Google Scholar 

  3. Kauzmann, W., Adv. Prot. Chem., 14, 1 (1959).

    CAS  Google Scholar 

  4. Kendrew, J. C., Brookhaven Symp. Biol., 15, 216 (1962).

    CAS  PubMed  Google Scholar 

  5. Perutz, M. F., J. Mol. Biol., 13, 646 (1965).

    Article  CAS  Google Scholar 

  6. Perutz, M. F., Kendrew, J. C., and Watson, H. C., J. Mol. Biol., 13, 669 (1965).

    Article  CAS  Google Scholar 

  7. Fisher, H. F., Proc. U.S. Nat. Acad. Sci., 51, 1285 (1964).

    Article  ADS  CAS  Google Scholar 

  8. Blake, C. C. F., Koenig, D. F., Mair, G. A., North, A. C. T., Phillips, D. C., and Sarma, V. R., Nature, 206, 757 (1965).

    Article  ADS  CAS  Google Scholar 

  9. Nirenberg, M. W., Jones, O. W., Leder, P., Clark, B. F. C., Sly, W. S., and Pestka, S., Cold Spring Harb. Symp. Quant. Biol., 28, 549 (1963).

    Article  CAS  Google Scholar 

  10. Brimacombe, R., Trupen, J., Nirenberg, M., Leder, P., Bernfield, M., and Jaoumi, R., Proc. U.S. Nat. Acad. Sci., 54, 954 (1965).

    Article  ADS  CAS  Google Scholar 

  11. Woese, C. R., Proc. U.S. Nat. Acad. Sci., 54, 71 (1965).

    Article  ADS  CAS  Google Scholar 

  12. Volkenstein, M. V., Nature, 207, 294 (1965).

    Article  ADS  CAS  Google Scholar 

  13. Pelc, S. R., Nature, 207, 597 (1965).

    Article  ADS  CAS  Google Scholar 

  14. Konigsberg, W., and Hill, R. J., J. Biol. Chem., 237, 3157 (1962).

    CAS  PubMed  Google Scholar 

  15. Beale, D., and Lehmann, H., Nature, 207, 259 (1965).

    Article  ADS  CAS  Google Scholar 

  16. Ingram, V. M., Nature, 187, 704 (1961).

    Article  ADS  Google Scholar 

  17. Schroeder, W. A., Shelton, J. R., Shelton, J. B., Cormick, J., and Jones, R. T., Biochem., 2, 992 (1963).

    Article  CAS  Google Scholar 

  18. Freese, E., and Yoshida, A., in Evolving Genes and Proteins, edit. by Bryson, V., and Vogel, H. J., 377 (New York, Academic Press, 1965).

    Google Scholar 

  19. Margoliash, E., and Smith, E., in Evolving Genes and Proteins, edit. by Bryson, V., and Vogel, H. J., 221 (New York, Academic Press, 1965).

    Book  Google Scholar 

  20. Stretton, A. O. W., and Brenner, S., J. Mol. Biol., 12, 456 (1965).

    Article  CAS  Google Scholar 

  21. Sonneborn, R. M., in Evolving Genes and Proteins, edit. by Bryson, V., and Vogel, H. J., 377 (New York, Academic Press, 1965).

    Book  Google Scholar 

  22. Woese, C. R., Proc. U.S. Nat. Acad. Sci., 54, 1546 (1965).

    Article  ADS  CAS  Google Scholar 

  23. Versteeg, D. H. G., and Vliegenthart, J. F. G., Experientia, 21, 615 (1965).

    Article  CAS  Google Scholar 

Download references

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EPSTEIN, C. Role of the Amino-Acid ‘Code’ and of Selection for Conformation in the Evolution of Proteins. Nature 210, 25–28 (1966). https://doi.org/10.1038/210025a0

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