Abstract
CHRISTIANSEN1 has objected to the “half-chair” conformation (C2 symmetry) of cyclohexane as the transition form for inversion of the chair conformation (presumably through the twisted boat) as proposed by one of us2. Earlier calculations3 had already indicated that the route through the boat (or twist-boat) form would permit inversion of the chair form of cyclohexane with lower activation energy than that of the planar hexagon.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on SpringerLink
- Instant access to the full article PDF.
USD 39.95
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Christiansen, J. A., Nature, 211, 184 (1966).
Hendrickson, J. B., J. Amer. Chem. Soc., 83, 4537 (1961).
Beckett, C. W., Pitzer, K. S., and Spitzer, R., J. Amer. Chem. Soc., 69, 2488 (1957).
Jensen, F. R., Noyce, D. S., Sederholm, C. H., and Berlin, A. J., J. Amer. Chem. Soc., 84, 386 (1962).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
HENDRICKSON, J., PITZER, K. Transition State in the Inversion of Cyclohexane. Nature 212, 749 (1966). https://doi.org/10.1038/212749a0
Received:
Issue date:
DOI: https://doi.org/10.1038/212749a0
