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Histidine Decarboxylase Inhibitors and the Survival of Skin Homografts

Nature volume 215, pages 871–872 (1967)Cite this article

Abstract

CHANG and I (unpublished results) have observed that skin homografting in rats results in a significant increase in urine histamine excretion and that the greatest histamine excretion occurs within a 3 day period of the observed time of graft rejection. The possibility that intracellular histamine metabolism and histamine formation from histidine decarboxylase activity might be involved in the mechanics of homograft rejection led to the present study of the effect of histidine decarboxylase inhibitors on rat skin homograft survival.

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References

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Authors and Affiliations

  1. Department of Surgery, Medical College of Virginia, Richmond, Virginia

    THOMAS C. MOORE

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  1. THOMAS C. MOORE
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MOORE, T. Histidine Decarboxylase Inhibitors and the Survival of Skin Homografts. Nature 215, 871–872 (1967). https://doi.org/10.1038/215871a0

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