Abstract
THE human I blood group system has several unusual features. The foetus and newborn have relatively strong i antigens on their red cells, and during the first 18 months of life this gradually converts to the adult status of a strong I antigen and a weaker i antigen1. The red cells of very rare adults retain the foetal i state2. Very little is known about the chemical nature of the red cell I antigen except that it probably contains carbohydrate3.
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References
March, W. L., Brit. J. Haematol, 7, 200 (1961).
Wiener, A. S., Unger, L. J., Cohen, L., and Feldman, J., Ann. Intern. Med., 44, 221 (1956).
Marcus, D. M., Zabat, B. A., and Rosenfield, R. E., J. Exp. Med., 118, 175 (1963).
Adinolfi, M., Immunology, 9, 43 (1965).
Channock, R. M., Mufson, M. A., Somerson, N. L., and Couch, R. B., Amer. Rev. Resp. Dis., 88, Suppl. 2, 218 (1963).
Jenkins, W. L., Koster, H. G., Marsh, W. L., and Carter, R. L., Brit. J. Haematol., 11, 480 (1965).
Dacie, J. V., The Haemolytic Anaemias: Congenital and Acquired, Part 2, The Autoimmune Haemolytic Anaemias, second ed. (churchill, London, 1962).
Cooper, A. G., Clin. Exp. Immunol., 3, 691 (1968).
Cohen, S., and Cooper, A. G., Immunology, 15, 93 (1968).
Edman, P., and Cooper, A. G., FEES Lett., 2, 33 (1968).
Marsh, W. L., Ried, M., and Nichols, M., Transfusion, 9, 280 (1969).
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COOPER, A. Soluble Blood Group I Substance in Human Amniotic Fluid. Nature 227, 508–509 (1970). https://doi.org/10.1038/227508a0
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DOI: https://doi.org/10.1038/227508a0


