Abstract
ALTHOUGH the parasitology of malaria has been extensively studied1, biochemical aspects of the relationships between the intra-erythrocytic parasite and its host erythrocyte are poorly understood. The main source of metabolic energy for the erythrocytic stages of the parasite is the breakdown of glucose with formation of lactic acid2–6, which it may carry out independently of the red cell2. Catabolism of glucose by metabolic pathways other than glycolysis may occur, although the overall pattern of glucose breakdown appears to vary with the species of malaria parasite7. The ability of the parasite, as distinct from the erythrocyte, to carry out the reactions of the pentose phosphate pathway is unresolved8–11,19.
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SHAKESPEARE, P., TRIGG, P. Glucose Catabolism by the Simian Malaria Parasite Plasmodium knowlesi. Nature 241, 538–540 (1973). https://doi.org/10.1038/241538a0
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DOI: https://doi.org/10.1038/241538a0
