Abstract
The two techniques for detecting human enzymes in man/mouse cell hybrids described here provide a promising and interesting approach to the mapping of chromosomal genes coding for mitochondrial enzymes. The authors confirm the nuclear gene specification of citrate synthase and malate dehydrogenase, and give information on their possible linkage with each other and with other genetic markers.
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VAN HEYNINGEN, V., CRAIG, I. & BODMER, W. Genetic Control of Mitochondrial Enzymes in Human–Mouse Somatic Cell Hybrids. Nature 242, 509–512 (1973). https://doi.org/10.1038/242509a0
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DOI: https://doi.org/10.1038/242509a0
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