Abstract
RAT epididymal fat cells respond to enterotoxins of Vibrio cholerae and Escherichia coli with increased membrane adenyl cyclase activity and glycerol release1–3. Cholera toxin increases adenyl cyclase activity in many other tissues and cells, including intestine, leukocytes, immunocytes, platelets and liver4–6. Here we report studies on the response of fat cells to these bacterial toxins and their effect on membrane adenyl cyclase activation by adrenaline.
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HEWLETT, E., GUERRANT, R., EVANS, D. et al. Toxins of Vibrio cholerae and Escherichia coli stimulate adenyl cyclase in rat fat cells. Nature 249, 371–373 (1974). https://doi.org/10.1038/249371a0
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DOI: https://doi.org/10.1038/249371a0
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