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Two distinct patterns of visual evoked response asymmetry in human albinism

Abstract

Results are presented which confirm that in human albinos each cerebral hemisphere receives a predominantly monocular input from the contralateral eye, giving rise to an asymmetry of the visual evoked potential (VEP) to whole-field stimulation which is similar to that for stimulation of the temporal half-field in the same individual. The further finding of two distinct, and in some respects opposite, types of topographical asymmetry raises the possibility that there are two anatomically distinct variants in the retinocortical projection in human albinism, as there are in the Siamese cat.

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References

  1. Guillery, R. W. Brain Res. 14, 739–741 (1969).

    Article  CAS  Google Scholar 

  2. Guillery, R. W. Brain Res. 33, 482–485 (1971).

    Article  CAS  Google Scholar 

  3. Cunningham, T. J. & Lund, R. D. Brain Res. 34, 394–398 (1971).

    Article  CAS  Google Scholar 

  4. Creel, D. J. & Giolli, R. A. Expl Neural. 36, 411–425 (1972).

    Article  CAS  Google Scholar 

  5. Sanderson, K. J. Anat. Rec. 172, 398 (1972).

    Google Scholar 

  6. Guillery, R. W. & Kaas, J. H. Science 180, 1287–1289 (1973).

    Article  ADS  CAS  Google Scholar 

  7. Giolli, R. A. & Guthrie, M. D. J. comp. Neural. 136, 99–125 (1969).

    Article  CAS  Google Scholar 

  8. Guillery, R. W., Okoro, A. N. & Witkop, C. J. Brain Res. 96, 373–377 (1975).

    Article  CAS  Google Scholar 

  9. Hubel, D. H. & Wiesel, T. N. J. Physiol., Lond. 218, 33–62 (1971).

    Article  CAS  Google Scholar 

  10. Kaas, J. H. & Guillery, R. W. Brain Res. 59, 61–95 (1973).

    Article  CAS  Google Scholar 

  11. Cooper, M. L., Blasdel, G. G. & Pettigrew, J.D. Assoc. Res. Vision Ophthalmol. Abstr., 216 (1978).

  12. Creel, D. J., Witkop, C. J. & King, R. A. Inv. Ophthalm. 13, 430–440 (1974).

    CAS  Google Scholar 

  13. Creel, D. J., O'Donnell, F. E. & Witkop, C. J. Science 201, 931–933 (1978).

    Article  ADS  CAS  Google Scholar 

  14. Creel, D. J. J. Biomed. Engng 1, 100–104 (1979).

    Article  CAS  Google Scholar 

  15. Barrett, G., Blumhardt, L. D., Halliday, A. M., Halliday, E. & Kriss, A. Nature 261, 253–255 (1976).

    Article  ADS  Google Scholar 

  16. Blumhardt, L. D. & Halliday, A. M. Expl Brain Res. 36, 53–69 (1979).

    Google Scholar 

Download references

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Carroll, W., Jay, B., McDonald, W. et al. Two distinct patterns of visual evoked response asymmetry in human albinism. Nature 286, 604–606 (1980). https://doi.org/10.1038/286604a0

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