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Laser biology and medicine
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  • Lasers Review
  • Published: 25 July 1985

Laser biology and medicine

  • V. S. Letokhov1 

Nature volume 316, pages 325–330 (1985)Cite this article

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Abstract

The substantial repertoire of laser radiation—its coherence, range of intensity and frequency, controlability of focal area and of beam length—has been comprehensively explored in the contexts of micro- and macro-diagnostics of cells, biochemical kinetics, therapy and surgery.

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References

  1. Basov, N. G., Prokhorov, A. M. & Townes, C. H. Nobel Lectures (Noble Foundation, Stockholm, 1962).

    Google Scholar 

  2. Schawlow, A. L. & Townes, C. H. Phys. Rev. 112, 1940–1949 (1958).

    Article  ADS  CAS  Google Scholar 

  3. Maiman, T. H. Nature 187, 493 (1960).

    Article  ADS  Google Scholar 

  4. Fine, S. & Klein, E. Laser Focus 5, 28–40 (1969).

    Google Scholar 

  5. Wolbarsht, M. L. (ed.) Laser Applications in Medicine and Biology Vols 1–3 (Plenum, New York, 1971, 1974, 1977).

  6. Berns, M. W. in Photochemical and Photo-Biological Reviews Vol. 2 (ed. smith, K. C.) 1–38 (Plenum, New York, 1977).

    Book  Google Scholar 

  7. Pratesi, R. & Sacchi, C. A., eds Lasers in Photomedicine and Photobiology (Springer, Berlin, 1980).

    Google Scholar 

  8. Goldman, L. (ed.) The Biomedical Laser. Technology and Clinical Applications (Springer, Berlin, 1981).

    Google Scholar 

  9. Smith, K. C. (ed.) The Science of Photobiology (Plenum, New York, 1977).

  10. Giese, A. C. (ed.) Photophysiology Vol. 1–8 (Academic, New York, 1964-73).

  11. Rentzepis, P. M. Science 202, 174–182 (1978).

    Article  ADS  CAS  Google Scholar 

  12. Letokhov, V. S. Nature 305, 103–108 (1983).

    Article  ADS  CAS  Google Scholar 

  13. KJiger, D. S. (ed.) Ultrasensitive Laser Spectroscopy (Academic, New York, 1983).

  14. Letokhov, V. S. (ed.) Laser Analytical Spectrochemistry (Hilger, London, in the press).

  15. Letokhov, V. S. Optica Acta (in the press).

  16. Bekov, G. I., Letokhov, V. S. & Radayev, V. N. Laser Chem. 5, 11–17 (1984).

    Article  CAS  Google Scholar 

  17. Bradley, A. B. & Zare, R. N. J. Am. chem. Soc. 98, 620 (1976).

    Article  CAS  Google Scholar 

  18. Antonov, V. S., Letokhov, V. S. & Shibanov, A. N. J. opt. Soc. Am. B. (in the press).

  19. Doiron, D. R. & Profio, A. E., in Lasers in Photomedicine and Photobiology (eds Pratesi, R.& Sacchi, C.) 92–95 (Springer, Berlin, 1980).

    Book  Google Scholar 

  20. Kittrell, C., Willett, R. L., de los Santos, C., Rat'liff, N. B. & Feld, M. S. Appl. Opt. (in the press).

  21. Landers, M. B. & Wolbrasht, M. L. in The Biomedical Laser (ed. Goldman, L.) 117 (Springer, Berlin, 1981).

    Book  Google Scholar 

  22. Peterson, J. I. & Vurek, G. G. Science 224, 123 (1984).

    Article  ADS  CAS  Google Scholar 

  23. Kaufmann, R. & Hillenkamp, F. & Wechsung, R. Med. Progr. Technol. 6, 106 (1979).

    Google Scholar 

  24. Andreoni, A., Longini, A., Sacci, C. A. & Svelto, O. in The Biomedical Laser (ed. Goldman, L.) 69–83 (Springer, Berlin, 1981).

    Book  Google Scholar 

  25. Letokhov, V. S. in Tunable Lasers and Applications Vol. 3 (eds Mooradian, A., Jaeger, T. & Stokseth, R.) 122–139 (Springer, Berlin, 1976); Comm. At. molec. Phys. 11, 1–12 (1982).

    Book  Google Scholar 

  26. Balykin, V. I. et al. Laser Spectroscopy, VI (eds Wever, H. P. & Lüthy, W.) 103–105 (Springer, Berlin, 1983).

    Book  Google Scholar 

  27. Shank, C. V. Science 219, 1027–1031 (1983).

    Article  ADS  CAS  Google Scholar 

  28. Alfano, R. R. (ed.) Biological Events Probed by Ultrafast Laser Spectroscopy (Academic, New York, 1982).

  29. Mullaney, P. F., Steinkamp, J. A., Crissman, H. M., Cram, L. S. & Holm, D. H. in Laser Applications in Medicine and Biology (ed. Woolbarsht, M. L.) Vol. 2, 151 (Plenum, New York, 1974).

    Book  Google Scholar 

  30. Salzman, G. C. in The Biomedical Laser (ed. Goldman, L.) 33–53 (Springer, Berlin, 1981).

    Book  Google Scholar 

  31. Stern, M. D. Nature 254, 56–58 (1975).

    Article  ADS  CAS  Google Scholar 

  32. Riva, C. E., Feke, G. T. in The Biomedical Laser (ed. Goldman, L.) 135–161 (Springer, Berlin, 1981).

    Book  Google Scholar 

  33. Tanaka, T., Benedek, G. B. Appl. Opt. 14, 189–196 (1975).

    Article  ADS  CAS  Google Scholar 

  34. Sattelle, D. B., Lee, W. I. & Ware, B. R. eds Biomedical Applications of Laser Light Scattering (Elsevier, Amsterdam, 1982).

  35. Gabor, D. Nature 161, 777 (1948).

    Article  ADS  CAS  Google Scholar 

  36. von Bally, G. (ed.) Holography in Medicine and Biology, Vol. 18, (Springer, Berlin, 1979).

  37. Fujimoto, J. G. et al. Adv. Prog. Conf. Lasers Electro-Optics 45 (Baltimore, 1985).

  38. Letokhov, V. S. Nonlinear Laser Chemistry, Multiple Photon Excitation Vol. 22 (Springer, Berlin, 1983).

    Book  Google Scholar 

  39. Brown, A. K. & McDonagh, A. F. Adv. Periatr 27, 341–389 (1980).

    CAS  Google Scholar 

  40. Parrish, J. A. J. invest. Dermal. 77, 167 (1981).

    Article  CAS  Google Scholar 

  41. Dougherty, T. J., Thoma, R. E., Boyle, D. G. & Weishaupt, K. P. in Lasers in Photomedicine and Biology (eds Pratesi, R. & Sacchi, C. A.) 67–75 (Springer, Berlin, 1980).

    Book  Google Scholar 

  42. Spikes, J. & MacKnight, F. Ann. N.Y. Acad. Sci. 171, 149–162 (1970).

    Article  ADS  CAS  Google Scholar 

  43. Hearst, J. E. in Chemical and Biochemical Applications of Lasers (ed. Moore, C. B.) Vol. 4, 389–403 (Academic, New York, 1979).

    Book  Google Scholar 

  44. Johnston, B. H., Johnson, M. A., Moore, C. B. & Hearst, J. E. Science 197, 906–908 (1977).

    Article  ADS  CAS  Google Scholar 

  45. Harrison, C. A., Turner, D. H. & Hinkle, D. C. Nucleic Acids Res. 10, 239–281 (1982).

    Article  Google Scholar 

  46. Gamaleya, N. F. in The Biomedical Laser (ed. Goldman, L.) 271 (Springer, Berlin, 1981).

    Book  Google Scholar 

  47. Mester, E. et al. in Medizinische Erfahrungen in Forschung und Praxis (ed. A. Kaul) 117 (De Gruyter, Amsterdam, 1976).

    Google Scholar 

  48. Lobko, V. V., Karu, T. J. & Letokhov, V. S. Biophysica (Russia) 30, 380–388 (1985).

    Google Scholar 

  49. Karu, T. J., Kalendo, G. S., Letokhov, V. S. & Lobko, V. V. Il nuovo Cimento D1, 828–840 (1982); D3, 309–318 (1984); D3, 319–325 (1984).

    Article  Google Scholar 

  50. Letokhov, V. S. J. Photochem. 4, 185–191 (1975).

    Article  CAS  Google Scholar 

  51. Kryukov, P. G., Letokhov, V. S., Matveetz Yu, A., Nikogosyan, D. N. & Sharkov, A. V. in Picosecond Phenomena Vol. 4 (eds Shank, C. V., Ippen, E. P. & Shapiro, S. L.) 158–166 (Springer, Berlin, 1978).

    Book  Google Scholar 

  52. Kryukov, P. G. et al. Chem. Phys. Lett. 61, 375–379 (1979).

    Article  ADS  CAS  Google Scholar 

  53. Nikogosyan, D. N., Oravesky, A. A. & Letokhov, V. S. Proc. USSR Acad. Sci. (in the press).

  54. Oravsky, A. A., Nikogosyan, D. N. & Letokhov, V. S. Lasers in the Life Sci. (in the press).

  55. Gurzadyan, G. G. et al. Photochem. Photobiol. 33, 835–838 (1981).

    Article  CAS  Google Scholar 

  56. Calmettes, P. P. & Berns, M. W. Proc. natn. Acad. Sci. U.S.A. 80, 7197–7199 (1983).

    Article  ADS  CAS  Google Scholar 

  57. Nikogosyan, D. N. & Letokhov, V. S. Revista nuovo Cimento 6, ser. 3, No. 8 (1983).

  58. Brash, D. E. & Haseltine, W. A. Nature 298, 189–192 (1982).

    Article  ADS  CAS  Google Scholar 

  59. Andreoni, A., Cubeddu, R., de Silvestri, S., Laporta, P. & Svelto, O. Phys. Rev. Lett. 45, 431 (1980).

    Article  ADS  CAS  Google Scholar 

  60. Benimetskaya, L. Z. et al. FEBS Lett. 163, 144–149 (1983).

    Article  CAS  Google Scholar 

  61. Barashev, P. P., Demidov, V. V., Tal'rose, V. L. & Trofimov, V. I. Proc. USSR Acad. Sci. 266, 1486–1490 (1982).

    CAS  Google Scholar 

  62. Karu, T. J., Kryukov, P. G., Ketokhov, V. S., Matveetz Yu, A. & Semichishen, V. A. Appl. Phys. 24, 245–247 (1981).

    Article  ADS  CAS  Google Scholar 

  63. Andreoni, A., Cubeddu, R., de Silvestri, S., Laporta, P. & Svelto, O. Chem. phys. Lett. 88, 37–39 (1982).

    Article  ADS  CAS  Google Scholar 

  64. Bridges, T. J. et al. Science 219, 1217–1219 (1983).

    Article  ADS  CAS  Google Scholar 

  65. Mainster, M. A., Sliney, D. H., Belcher, C. D. III, & Buzney, S. M. Ophthalmology 90, 973–991 (1983).

    Article  CAS  Google Scholar 

  66. Berns, M. W., Oison, R. S. & Rounds, D. E. Nature 221, 74–75 (1969).

    Article  ADS  CAS  Google Scholar 

  67. Wolbarsht, M. L. & Landers, M. B. III Appl. Opt. 18, 1518–1526 (1979).

    Article  ADS  CAS  Google Scholar 

  68. Krasnov, M. M. Am. J. Opth. 75, 674 (1975).

    Article  Google Scholar 

  69. Lee, G., Ikeda, R. M., Kozina, J. & Mason, D. T. Am. Heart J. 102, 1074–1077 (1981).

    Article  CAS  Google Scholar 

  70. Choy, D. S., Stretzer, S. H., Rotterdam, H. Z. & Bruno, M. S. Am. J. Card. 50, 1209 (1982).

    Article  CAS  Google Scholar 

  71. Srinivasan, R. & Leigh, W. J. J. Am. chem. Soc. 104, 6784 (1982).

    Article  CAS  Google Scholar 

  72. Grundfest, W. et al. Circulation 70, Suppl. II (1984).

  73. Kinsker, R., Srinivasan, R., Wynne, J. J. & Alonso, D. R. Lasers in Surgery and Medicine (in the press).

  74. Abil'siitov, G. A. et al. Kvantovaya Elektronika (in the press).

  75. Berns, M. W. et al. Science 213, 505–513 (1981).

    Article  ADS  CAS  Google Scholar 

  76. Tsukakoshi, M. et al. Appl. Phys. B 35, 135–140 (1984).

    Article  ADS  Google Scholar 

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Author information

Authors and Affiliations

  1. Institute of Spectroscopy and Laser Technology Centre of the USSR Academy of Sciences, Moscow, Podolskii Rayon, Troitzk, 142092, USSR

    V. S. Letokhov

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  1. V. S. Letokhov
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Letokhov, V. Laser biology and medicine. Nature 316, 325–330 (1985). https://doi.org/10.1038/316325a0

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  • Issue date: 25 July 1985

  • DOI: https://doi.org/10.1038/316325a0

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