The development of a cytomorphologic infectivity microbioassay for human immunodeficiency virus (HIV) allows rapid, sensitive, and specific characterization of neutralizing antibodies or antiviral agents.
Enjoying our latest content?
Log in or create an account to continue
- Access the most recent journalism from Nature's award-winning team
- Explore the latest features & opinion covering groundbreaking research
or
References
Ho, D.D., Pomerantz, R.J. & Kaplan, J.C. New Engl. J. Med. 317, 278–286 (1987).
Delbrück, M. J. Bact. 50, 137–150 (1945).
Dulbecco, R. Proc. natn. Acad. Sci. U.S.A. 38, 747–752 (1952).
Dulbecco, R., Vogt, M., & Strickland, A.G.R. Virology 2, 162–205 (1956).
Nara, P.L. et al. AIDS Res. Hum. Retroviruses 3, 283–302 (1987).
Sodroski, J., Goh, W.C., Rosen, C., Campbell, K. & Haseltine, W. A. Nature 322, 470 (1986).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Nara, P., Fischinger, P. Quantitative infectivity assay for HIV-1 and -2. Nature 332, 469–470 (1988). https://doi.org/10.1038/332469a0
Issue date:
DOI: https://doi.org/10.1038/332469a0
This article is cited by
-
A functional conserved intronic G run in HIV-1 intron 3 is critical to counteract APOBEC3G-mediated host restriction
Retrovirology (2014)
-
Quantification of HIV-based lentiviral vectors: influence of several cell type parameters on vector infectivity
Archives of Virology (2012)
-
Inhibition of HIV-1 endocytosis allows lipid mixing at the plasma membrane, but not complete fusion
Retrovirology (2011)
-
APOBEC3G induces a hypermutation gradient: purifying selection at multiple steps during HIV-1 replication results in levels of G-to-A mutations that are high in DNA, intermediate in cellular viral RNA, and low in virion RNA
Retrovirology (2009)
-
Antagonistic interaction of HIV-1 Vpr with Hsf-mediated cellular heat shock response and Hsp16 in fission yeast (Schizosaccharomyces pombe)
Retrovirology (2007)
