Figure 11
From: Matrix metalloproteinases, tissue inhibitors of MMPs and TACE in experimental cerebral malaria
Comparison of the expression of MMPs, TACE and TIMPs in CM and non-CM. C57Bl/6 mice were infected with P. berghei ANKA (resulting in CM) or with P. berghei NK65 (non-CM), and Balb/C mice were infected with P. berghei ANKA (non-CM). RNA was extracted from the brains (n=3 for each condition) and RT-PCR was performed to analyse the expression of MMPs and TACE (a) and of TIMPs (b). 18S mRNA was used as a control for the quantification of total mRNA. *P<0.05; **P<0.02; ***P<0.001. Con, uninfected control; D8, 8 days after infection.
