Figure 4
X-tile plot of Met nuclear expression, optimal cut-point selection by training and validation set. X-tile plot representing all possible cut-points for the training set (a) and validation set (c) of nuclear Met data. Each colored pixel is a single cut-point where patient number increases down the plot for high expressers or to the right for low expressers. The intensity and color of the pixel represents the direction of the relationship with patient survival. (Red represents better outcome for the lower population.) Histograms depict the population distribution in the training set (b) and validation set (d) with their Kaplan–Meier plots as determined using the X-tile optimal cut-point of 0.4. Red represents low expressers and green represents high expressers.
