Table 3 Multivariate analysis of breast cancer samples at 5-year survival. Multivariate analysis N=257 (Validation set split at cut-point generated by X-tile
Variable | Risk ratio (95% confidence interval) | P |
|---|---|---|
(a) | ||
Nodal status | ||
Node positive | 1.00 | |
Node negative | 2.63 (1.55–4.64) | 0.0002 |
Nuclear grade | ||
1 | 1.00 | |
2 | 1.20 (0.59–2.70) | |
3 | 1.26 (0.74–2.13) | 0.5205 |
Tumor size | ||
⩽2 cm | 1.00 | |
>2 cm | 1.74 (1.07–2.89) | 0.0261 |
ER | ||
Low (0) | 1.00 | |
High (1 to 3+) | 0.49 (0.29–0.83) | 0.0072 |
PR | ||
Low (0) | 1.00 | |
High (1 to 3+) | 0.64 (0.37–1.08) | 0.0991 |
Her2 | ||
Low (0 to 2) | 1.00 | |
High (3+) | 2.12 (1.08–3.89) | 0.0304 |
Met (nuclear) | ||
Low | 1.00 | |
High | 1.30 (0.79–2.14) | 0.2891 |
(b) | ||
ER | ||
Low (0) | 1.00 | |
High (1 to 3+) | 1.35 (1.06–1.76) | 0.0166 |
PR | ||
Low (0) | 1.00 | |
High (1 to 3+) | 1.29 (0.99–1.68) | 0.0525 |
Her2 | ||
Low (0–2) | 1.00 | |
High (3+) | 0.77 (0.58–1.07) | 0.1107 |
Met (nuclear) | ||
Low | 1.00 | |
High | 1.72 (1.09–2.74) | 0.0206 |
(c) | ||
Nodal status | ||
Node positive | 1.00 | |
Node negative | 0.60 (0.47–0.77) | <0.0001 |
ER | ||
Low (0) | 1.00 | |
High (1 to 3+) | 1.32 (1.03–1.71) | 0.0238 |
PR | ||
Low (0) | 1.00 | |
High (1 to 3+) | 1.28 (0.99–1.67) | 0.0528 |
Her2 | ||
Low (0 to 2) | 1.00 | |
High (3+) | 0.71 (0.53–0.99) | 0.0460 |
Met (nuclear) | ||
Low | 1.00 | |
High | 1.58 (1.00–2.52) | 0.0512 |
(d) | ||
Tumor size | ||
⩽2 cm | 1.00 | |
>2 cm | 0.74 (0.59–0.94) | 0.0121 |
ER | ||
Low (0) | 1.00 | |
High (1 to 3+) | 1.40 (1.09–1.82) | 0.0072 |
PR | ||
Low (0) | 1.00 | |
High (1 to 3+) | 1.27 (0.98–1.65) | 0.0690 |
Her2 | ||
Low (0 to 2) | 1.00 | |
High (3+) | 0.75 (0.56–1.05) | 0.0914 |
Met (nuclear) | ||
Low | 1.00 | |
High | 1.64 (1.04–2.61) | 0.0345 |
