Figure 3 | Laboratory Investigation

Figure 3

From: Knockout of α-calcitonin gene-related peptide reduces cholangiocyte proliferation in bile duct ligated mice

Figure 3

(a) The message for α-CGRP was expressed in normal and BDL WT cholangiocytes with a significant increase observed in BDL WT. There was also a significant increase in the β-CGRP message in BDL KO cholangiocytes. (b) Cholangiocytes isolated from normal and BDL WT and KO mice express mRNA for CGRP receptor components, CLR, RCP, and RAMP1. Upregulation of receptor expression was observed in BDL WT and KO mice. Data are mean±s.e.m. of n=3 experiments. *P<0.05 vs normal WT. #P<0.05 vs BDL WT.

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