Table 1 VHL mutational analysis of CC-RCC samples with positive nuclear E-cadherin staining
Patient no. | VHL mutation | VHL staining | Membranous E-cadherin staining | Furhman grade | Pathological stage | Tumor size (cm) |
|---|---|---|---|---|---|---|
1 | N/A | − | − | 2 | T1b | 5.0 |
2 | Exon 1-c.163_164 ins G | + | + | 2 | T1a | 2.0 |
3 | N/A | + | + | 2 | T1a | 2.5 |
4 | Exon 1-c.163G>T(E55X) | + | + | 2 | T1b | 4.5 |
5 | N/A | + | + | 2 | T1b | 4.8 |
6 | Exon 2-c.444 del T | + | + | 2 | T1b | 4.1 |
7 | Exon 2-g.5386_5396 del 11 | + | ± | 2 | T3a | 7.2 |
8 | WT* | + | + | 2 | T1a | 3.0 |
9 | Exon 2-c.407T>C(F136S) | + | + | 2 | T1a | 2.5 |
10 | Exon 3-c.509 del T ins CG | + | + | 2 | T1b | 4.5 |
11 | WT | + | + | 2 | T1a | 2.1 |
12 | N/A | + | ± | 2 | T1a | 2.2 |
13 | WT | + | + | 2 | T1a | 3.8 |
14 | Exon 1-c.203 C>A(S68X) | + | + | 2 | T1a | 1.8 |
15 | N/A | + | + | 2 | T1a | 1.8 |
16 | Exon 1-c.294C>G(Y98X) | + | + | 2 | T1b | 6.0 |
17 | Exon 3-c.533del (6) ins (7) | ± | + | 2 | T1a | 3.5 |
18 | Exon 1-c.247del G | − | − | 3 | T3b | 13.5 |
19 | Exon 1-c.233 A>T(N78I) | − | − | 3 | T2 | 8.0 |
20 | WT | + | + | 3 | T1a | 3.5 |
21 | WT | + | − | 3 | T1b | 6.0 |
22 | WT | ± | − | 3 | T3a | 12.0 |
