Figure 5

Quantification of p53 and c-Ha-ras mRNAs by densitometric analysis of Northern blots. Mean values ± sem obtained from individual densitometric measures are represented (n = 3). A, Quantification of p53 mRNA by densitometric analysis of the blots. After the adjustment for the respective 18S ribosomal signals, p53 was significantly up-regulated 8 hours after PH and temporary partial hepatectomy (TPH). B, Quantification of c-Ha-ras mRNA by densitometric analysis of the blots. After the adjustment for the respective 18S ribosomal signals, c-Ha-ras was only significantly up-regulated 24 hours after PH. *p < 0.05; **p < 0.01; ***p < 0.001.