Figure 3 | Laboratory Investigation

Figure 3

From: Expression of SHP-1 Phosphatase Indicates Post-Germinal Center Cell Derivation of B-Cell Posttransplant Lymphoproliferative Disorders

Figure 3

Histology and expression of SHP-1 and CD138 by representative PTLD cases. A, HE stains of PTLD, polymorphic type. B, Immunohistochemical staining for SHP-1 protein showing strong staining of the malignant-appearing cells. C, Lack of staining of the lymphoma cells for CD138 protein (the depicted plasma cell represents an internal positive control). D, HE of PTLD, monomorphic type with immunoblastic and plasmacytoid differentiation. E, SHP-1 stains showing that the lymphoma cells are strongly positive for the protein. F, Strong CD138 staining in the immunoblasts and plasmacytic cells.

Back to article page