Figure 1 | Laboratory Investigation

Figure 1

From: Apoptosis and Apoptosis-Related Molecules in the Submandibular Gland of the Nonobese Diabetic Mouse Model for Sjögren’s Syndrome: Limited Role for Apoptosis in the Development of Sialoadenitis

Figure 1

Apoptotic cells, present in the submandibular gland (SMG) of nonobese diabetic (NOD) and C57BL/10 mice, as detected by terminal deoxynucleotidyl transferase-mediated dUTP nick end labeling (TUNEL) assay. A, 5-week-old NOD mouse; B, 5-week-old C57BL/10 mouse; C, lymphocytic infiltrate, in SMG of 20-week-old NOD mouse; D, negative TUNEL control in which the TdT enzyme was omitted from the reaction mixture on SMG section of a 5-week-old NOD mouse (× 400).

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