Figure 1

Ductular cells and ductular hepatocytes in massive hepatic necrosis. Ductular cells (a and c) appear around the portal tract and show glandular or bile duct-like structures (Case 8 in Table 1). Ductular hepatocytes (b and d) show features between biliary epithelial cells (BEC) and hepatocytes and are intermingled with hepatocytes (Case 1 in Table 1). Intermingled hepatocytes show poor cytokeratin-7 (CK-7) staining (arrows indicate identical cells). a and b, hematoxylin and eosin staining; c and d, CK-7 staining; ×500.