Table 2 HNF Expression in Normal Livers and FH
Normal liver | Fulminant hepatitis | |||||
|---|---|---|---|---|---|---|
Biliary epithelial | Hepatocytes | Ductular cells | Ductular hepatocyte | Residual hepatocytes | Regenerative hepatocytes | |
HNF-1 | ||||||
Nuclear | 9/9 | 9/9 | 8/10 | 4/5 | 0/6 | 1/1 |
Cytoplasmic | 1/9 | 5/9 | 5/10 | 0/5 | 3/6 | 0/1 |
HNF-4α | ||||||
Nuclear | 0/9 | 9/9 | 7/10 | 5/5 | 1/6 | 1/1 |
Cytoplasmic | 0/9 | 1/9 | 6/10 | 1/5 | 2/6 | 0/1 |
HNF-3β | ||||||
Nuclear | 3/9 | 6/9 | 1/10 | 1/5 | 0/6 | 1/1 |
Cytoplasmic | 3/9 | 6/9 | 6/10 | 2/5 | 2/6 | 0/1 |
C/EBPα | ||||||
Nuclear | 0/9 | 2/9 | 0/10 | 1/5 | 0/6 | 1/1 |
Cytoplasmic | 2/9 | 7/9 | 3/10 | 1/5 | 2/6 | 0/1 |
AFP | − | − | + | + | − | − |
CK-7 | + | − | + | +/− | − | − |
