Table 1 Clinicopathological data and findings of defective mismatch-repair

From: Loss of mismatch repair protein immunostaining in colorectal adenomas from patients with hereditary nonpolyposis colorectal cancer

Adenoma number

Sex/age (years)

Size (mm)

Histology

Dysplasia grade

Adenoma location

Immunohistochemical staining

MSI status

Germline mutation

      

MLH1

PMS2

MSH2

MSH6

 

Gene

Codon

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  1. TA, tubular adenoma; TVA, tubulo-villous adenoma; SA, serrated adenoma; LG, low-grade; HG, high-grade; D, distal; P, proximal; ND, no data available; MSI, microsattelite instable; MSS, microsatellite stable; IH, immunohistochemistry. The shaded areas indicate different cases, some of which contain multiple tumors.