Figure 1
(a) CD30 expression in a case of mixed cellularity Hodgkin's lymphoma ( × 240, alkaline phosphatase-anti alkaline phosphatase). (b) Proliferation rate of Hodgkin's and Reed–Sternberg cells and reactive lymphocytes in the same lymph node as shown by repp86 expression with some negative tumor cells ( × 240, alkaline phosphatase-anti alkaline phosphatase). (c) Hodgkin's lymphoma with numerous Ki-67-positive Hodgkin's and Reed–Sternberg cells. Atypical mitosis in the center ( × 480, streptavidin–biotin complex). (d) Compared to Ki-67, low repp86 expression indicating the actual proliferation rate. Strong expression in proliferating lymphocytes as internal control ( × 480, alkaline phosphatase-anti alkaline phosphatase). (e) Hodgkin's and Reed–Sternberg cells with strong Ki-67 expression in a case of mixed cellularity Hodgkin's lymphoma ( × 480, streptavidin–biotin complex). (f) Same case as (e) the majority of Hodgkin's and Reed–Sternberg cells are negative for repp86 ( × 480, alkaline phosphatase-anti alkaline phosphatase).
