Table 2 MSI phenotype and TP53 defects in carcinosarcomas

From: DNA mismatch repair and TP53 defects are early events in uterine carcinosarcoma tumorigenesis

Case

Carcinoma

Sarcoma

 

MSI-H

TP53 defect

MSI-H

TP53 defect

165, 1161, 1208, 1239, 1338, 1467, 1469, 1491, 1595, 1596, 1634, 1728, 1765, 1860

+

+

1689

+

+

1643

+

+

+

+

160, 1210, 1354, 1461, 1630, 1850

1203, 1413

+

+

+

1144

+

+

+

1230

+

+

+

1828

+

1848

+

  1. +: Indicate MSI-high phenotype or TP53 defect by either 17p deletion analysis or immunohistochemical overexpression.