Table 4 Biomarker expression: correlation with clinicopathologic parameters in endometrial carcinoma

From: Steroid receptor coactivator AIB1 in endometrial carcinoma, hyperplasia and normal endometrium: correlation with clinicopathologic parameters and biomarkers

 

AIB1 (BDa)

ER

PR (total)

PRB-N

PRB-C

 

n

Median

K–W

WRS

n

Median

K–W

WRS

n

Median

K–W

WRS

n

Median

K–W

WRS

n

Median

K–W

WRS

   

P

P

  

P

P

  

P

P

  

P

P

  

P

P

Menopause

 Pre

13

80

0.002

 

14

265

0.84

 

15

255

0.28

 

14

105

0.79

 

14

200

0.42

 

 Peri

10

200

  

10

210

  

10

255

  

10

100

  

10

170

  

 Post

59

200

  

60

210

  

60

202.5

  

61

120

  

61

170

  

Stage

 I

54

200

 

0.09

55

230

 

0.02

56

240

 

0.004

56

130

 

0.31

56

195

 

0.69

 II–IV

18

190

  

18

160

  

18

120

  

18

85

  

18

160

  

Grade

 I

43

200

 

0.04

45

250

 

0.01

46

247.5

 

0.03

45

120

 

0.42

45

150

 

0.05

 II/III

38

270

  

38

200

  

38

195

  

39

100

  

39

200

  

Histo type

 I

67

200

 

0.07

68

210

 

0.48

69

210

 

0.21

69

120

 

0.09

69

170

 

0.08

 II

14

270

  

15

270

  

15

120

  

15

180

  

15

200

  
  1. K–W=Kruskal–Wallis test; WRS=Wilcoxon rank sum test; PRB-N=PR-B isoform nuclear expression; PRB-C=PR-B cytoplasmic expression.
  2. aBD Bioscience.
  3. Bold values indicate statistically significant P-values.