Figure 7 | Modern Pathology

Figure 7

From: The histopathology of fatal untreated human respiratory syncytial virus infection

Figure 7

Peribronchial and intraluminal lymphoid aggregates. Peribronchial lymphoid aggregates are primarily composed of CD20+ B lymphocytes, presumably part of the BALT. During the response to RSV infection, some areas appear to develop the appearance of a hyperplastic lymph node follicle (a). The hyperplastic lymphoid nodules, which extend into and partially obstruct the airway lumen, are also predominantly composed of CD20+ B lymphocytes (b). Occasional CD3+ lymphocytes are present in the hyperplastic nodules (c). CD68+ monocytes are sparse in hyperplastic nodules (d). All images are from the 1999 case; original magnifications × 25 (a), × 62.5 (bd).

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