TABLE 4 BTD Versus CH

From: Liver Pathology: Cirrhosis, Hepatitis, and Primary Liver Tumors. Update and Diagnostic Problems

 

BTD

CH

Disruption of terminal plate (“piecemeal”)

++

++

Cholangiolar proliferation

+++

+

Periportal copper deposition

++

Periportal hepatocyte rosettes

±

++

Pericellular mononuclear cuffing

±

++

Holly-leaf pattern of fibrosis

±

++

Cholestasis with bile plugs

DO

Bile infarcts, bile lakes

LBDO

  1. BTD, biliary tract disease; CH, chronic hepatitis; DO, duct obstruction; LBDO, large bile duct obstruction; +, present to a 1+ degree; ++, present to a 2+ degree; +++, present to a 3+ degree; −, not present; ±, minimal degree of involvement.
  2. From Ferrell LD. Liver and gallbladder pathology. In: Weidner N, editor. The difficult diagnosis in surgical pathology. Philadelphia: W.B. Saunders; 1996. p. 287. Reprinted with permission.