TABLE 1 Clinicopathologic Features of SMECE and MEC of Thyroid Gland
Case | Age/Sex | Clinical Findings/Treatment | Gross Findings | Histo-Dx | LT | IH | Tumor Extent/Mets | Follow-Up |
|---|---|---|---|---|---|---|---|---|
1 | 38/F | Right neck mass × 1 mo/Total-thyr and right neck dissection | Firm, white mass; 6 cm | SMECE | + | Thyrog −, calci −, kera + | Extension to skeletal muscle/11 of 13 LN + | NAD 3 mo |
2 | 47/F | Right thyroid mass × 2 y/Right-thyr | Circumscribed solid mass 5 cm | SMECE | + | Thyrog −, calci −, kera +, mucin + | Confined to thyroid | NAD 2 y |
3 | 73/F | Right thyroid mass/Right-thyr | 3-cm solid mass with 1-cm cyst | SMECE | + | Thyrog −, calci −, kera + | Confined to thyroid | NA |
4 | 64/F | Right thyroid nodule; hypothyroid/Right-thyr | Poorly defined gray area | SMECE | + | Thyrog −, calci −, kera + | Confined to thyroid | NA |
5 | 27/F | Cold nodule/Total-thyr | 2 cm | MEC | − | Thyrog +, calci −, kera +, mucin − | Confined to thyroid | NAD 7 y |
6 | 64/M | Right thyroid mass/Right-thyr followed by left-thyr | 10 cm | MEC +, tall cell, pap Ca | − | Thyrog +, calci −, kera + | Extensive lymphatic invasion by tall cell ca | DOD After 3 mo |
7 | 83/F | Right thyroid mass/Partial-thyr | NA | MEC +, anaplastic, ca | − | Thyrog +, calci −, kera +, mucin + | Widely invasive | Mets to lung DOD after 5 mo |
8 | 55/M | NA/Total-thyr & neck dissection | NA | MEC | − | Thyrog +, calci −, kera +, mucin + | NA | NA |
9 | 36/F | Left thyroid mass/Total-thyr | 1.6-cm firm discrete mass | MEC | + | Thyrog +, calci −, mucin +, kera + | Confined to thyroid | NA |