TABLE 1 Clinicopathologic Features of SMECE and MEC of Thyroid Gland

From: Primary Mucoepidermoid Carcinoma and Sclerosing Mucoepidermoid Carcinoma with Eosinophilia of the Thyroid Gland: A Report of Nine Cases

Case

Age/Sex

Clinical Findings/Treatment

Gross Findings

Histo-Dx

LT

IH

Tumor Extent/Mets

Follow-Up

1

38/F

Right neck mass × 1 mo/Total-thyr and right neck dissection

Firm, white mass; 6 cm

SMECE

+

Thyrog −, calci −, kera +

Extension to skeletal muscle/11 of 13 LN +

NAD 3 mo

2

47/F

Right thyroid mass × 2 y/Right-thyr

Circumscribed solid mass 5 cm

SMECE

+

Thyrog −, calci −, kera +, mucin +

Confined to thyroid

NAD 2 y

3

73/F

Right thyroid mass/Right-thyr

3-cm solid mass with 1-cm cyst

SMECE

+

Thyrog −, calci −, kera +

Confined to thyroid

NA

4

64/F

Right thyroid nodule; hypothyroid/Right-thyr

Poorly defined gray area

SMECE

+

Thyrog −, calci −, kera +

Confined to thyroid

NA

5

27/F

Cold nodule/Total-thyr

2 cm

MEC

Thyrog +, calci −, kera +, mucin −

Confined to thyroid

NAD 7 y

6

64/M

Right thyroid mass/Right-thyr followed by left-thyr

10 cm

MEC +, tall cell, pap Ca

Thyrog +, calci −, kera +

Extensive lymphatic invasion by tall cell ca

DOD After 3 mo

7

83/F

Right thyroid mass/Partial-thyr

NA

MEC +, anaplastic, ca

Thyrog +, calci −, kera +, mucin +

Widely invasive

Mets to lung DOD after 5 mo

8

55/M

NA/Total-thyr & neck dissection

NA

MEC

Thyrog +, calci −, kera +, mucin +

NA

NA

9

36/F

Left thyroid mass/Total-thyr

1.6-cm firm discrete mass

MEC

+

Thyrog +, calci −, mucin +, kera +

Confined to thyroid

NA

  1. Histo-Dx, histologic diagnosis; LT, lymphocytic thyroiditis; IH, immunohistochemistry; Mets, metastases; thyr, thyroidectomy; LN, lymph nodes; SMECE, sclerosing mucoepidermoid carcinoma with eosinophilia; MEC, mucoepidermoid carcinoma; thyrog, thyroglobulin; calci, calcitonin; kera, cytokeratin; NAD, no evidence of disease; DOD, died of disease; pap, papillary; ca, Carcinoma.