TABLE 3 Correlation of Immunophenotypic Profiles, Grade, and Genotype for Follicular Lymphomas

From: Immunophenotypic and Genotypic Markers of Follicular Center Cell Neoplasia in Diffuse Large B-Cell Lymphomas

 

Grade I

Grade II

Grade III

Bcl-2-Rb

Bcl-6-Rb

Bcl-6+, bcl-2+, CD10+

8

5

3

8/13a

2/12a

Bcl-6+, bcl-2+, CD10−

0

0

1

0/0

0/0

Bcl-6+, bcl-2−, CD10+

0

1

1

0/1

0/0

  1. All cases were CD138 negative. This table does not include two grade I (CD10+, bcl-2+) and one grade III (CD10− bcl-2 equivocal) follicular lymphoma because lacked bcl-6 stains. No molecular data is available for these three cases.
  2. aOne case had both bcl-2 and bcl-6 rearrangements.
  3. bOnly includes results for cases with documented immunoglobulin heavy-chain rearrangement.
Back to article page