FIGURE 1

A and C illustrate low-magnification appearance of Cases 1 and 3, respectively, demonstrating follicle center lymphoma with extensive marginal zone differentiation. In these cases, the marginal-zone component is paler than the follicle centers and fills the interfollicular area, making these cases ideal for microdissection studies. Panels B and D show the high-magnification appearance of the marginal-zone cells in Cases 1 and 3, respectively. The cells are small with moderate amounts of cytoplasm. Occasional larger cells with open chromatin are also present. Follicle center cells are shown in contrast in each panel (right upper corner in B and left side in D).