TABLE 1 Immunohistochemistry: p53, p21, and mdm-2

From: Transition from In Situ to Invasive Testicular Germ Cell Neoplasia is Associated with the Loss of p21 and Gain of mdm-2 Expression

 

Invasive Seminoma

Invasive Embryonal Carcinoma

 

p53

p21

mdm-2

p53

p21

mdm-2

Number of cases

17

17

17

14

14

14

Number positive

17

0

8

14

2

13

Tumor positivity (%)

100

0

47

100

14

93

Cellular positivity (%)

25

0

13

71

12

94

Staining intensity (0–3)

1.9

0.0

2.1

2.6

2.5

2.9

 

Intratubular Seminoma

Intratubular Embryonal Carcinoma

Number of Cases

14

14

14

13

13

13

Number Positive

13

9

1

13

9

1

Tumor Positivity (%)

93

64

7

100

69

8

Staining Intensity (0–3)

3.0

1.0

1.0

3.0

2.1

1.0

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