TABLE 2 Immunohistochemical phenotype of Desmoplastic Small Round Cell Tumors

From: Immunophenotype of Desmoplastic Small Round Cell Tumors as Detected in Cases with EWS-WT1 Gene Fusion Product

 

CAM5.2

AE1/3

DES

PLAP

MYO

MyoD

MYG

Myf5

CALR

MIC2

WT1

HER2

c-kit

N=

23

23

23

21

17

20

22

21

21

23

23

18

14

Neg

2

7

2

4

11

20

22

21

15

10

5

11

12

F+

4

4

3

4

1

0

0

0

3

1

2

0

2*

1+

3

7

6

6

4

0

0

0

1

5

2

4

0

2+

3

4

7

6

0

0

0

0

0

7

3

2

0

3+

11

1

5

1

0

0

0

0

0

0

9

1

0

 

21/23

16/23

21/23

17/21

5/17

   

4/21

13/23

16/23

7/18

2/14

Total+

(91%)

(70%)

(91%)

(81%)

(29%)

0

0

0

(19%)

(57%)

(70%)

(39%)

(14%)

  1. F ≤ 20%.
  2. 1+. Weak >20 but ≤ 50%.
  3. 2+. Weak >50%.
  4. Moderate >20% but ≤ 75%.
  5. Strong >20% but ≤ 50%.
  6. 3+ Moderate > 75%.
  7. Strong >50%.
  8. *Rare cells only.
  9. DES = desmin; MYO = myoglobin; MYG = myogenin; CALR = calretinin; PLAP = placental alkaline phosphatase.
Back to article page