Lipids can hop between cellular compartments without using the transport vesicles that carry proteins. A key molecule involved in conveying the lipid ceramide has at last been uncovered.
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References
Hanada, K. et al. Nature 426, 803–809 (2003).
Collins, R. N. & Warren, G. J. Biol. Chem. 267, 24906–24911 (1992).
Kok, J. W., Babia, T., Klappe, K., Egea, G. & Hoekstra, D. Biochem. J. 333, 779–786 (1998).
Yamaji, A. et al. J. Biol. Chem. 273, 5300–5306 (1998).
Fukasawa, M., Nishijima, M. & Hanada, K. J. Cell Biol. 144, 673–685 (1999).
Ponting, C. P. & Aravind, L. Trends Biochem. Sci. 24, 130–132 (1999).
Levine, T. P. & Munro, S. Curr. Biol. 12, 695–704 (2002).
Loewen, C. J., Roy, A. & Levine, T. P. EMBO J. 22, 2025–2035 (2003).
Lehto, M. & Olkkonen, V. M. Biochim. Biophys. Acta 1631, 1–11 (2003).
Adam, D., Heinrich, M., Kabelitz, D. & Schutze, S. Trends Immunol. 23, 1–4 (2002).
Wyles, J. P., McMaster, C. R. & Ridgway, N. D. J. Biol. Chem. 277, 29908–29918 (2002).
Pagano, R. E., Martin, O. C., Kang, H. C. & Haugland, R. P. J. Cell Biol. 113, 1267–1279 (1991).
Ladinsky, M. S., Mastronarde, D. N., McIntosh, J. R., Howell, K. E. & Staehelin, L. A. J. Cell Biol. 144, 1135–1149 (1999).
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Munro, S. Earthworms and lipid couriers. Nature 426, 775–776 (2003). https://doi.org/10.1038/426775a
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DOI: https://doi.org/10.1038/426775a
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