Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News Feature
  • Published:

Psychedelic drugs

The ups and downs of ecstasy

The clubbers' drug is now being studied as a treatment for anxiety and post-traumatic stress disorder. Erika Check charts its rocky road from the psychedelic underground to the psychiatric clinic.

This is a preview of subscription content, access via your institution

Relevant articles

Open Access articles citing this article.

Access options

Buy this article

USD 39.95

Prices may be subject to local taxes which are calculated during checkout

References

  1. Abraham, H. D., Aldridge, A. M. & Gogia, P. Neuropsychopharmacology 14, 285–298 (1996).

    Article  CAS  Google Scholar 

  2. Greer, G. & Tolbert, R. J. Psychoactive Drugs 18, 319–327 (1986).

    Article  CAS  Google Scholar 

  3. Ricaurte, G., Bryan, G., Strauss, L., Seiden, L. & Schuster, C. Science 229, 986–988 (1985).

    Article  ADS  CAS  Google Scholar 

  4. Ricaurte, G. A., DeLanney, L. E., Irwin, I. & Langston, J. W. Brain Res. 446, 165–168 (1988).

    Article  CAS  Google Scholar 

  5. Ricaurte, G. A. et al. J. Am. Med. Assoc. 260, 51–55 (1988).

    Article  CAS  Google Scholar 

  6. Ricaurte, G. A., DeLanney, L. E., Wiener, S. G., Irwin, I. & Langston, J. W. Brain Res. 474, 359–363 (1988).

    Article  CAS  Google Scholar 

  7. Green, A. R., Mechan, A. O., Elliott, J. M., O'Shea, E. & Colado, M. I. Pharmacol. Rev. 55, 463–508 (2003).

    Article  CAS  Google Scholar 

  8. McCann, U. D., Ridenour, A., Shaham, Y. & Ricaurte, G. A. Neuropsychopharmacology 10, 129–138 (1994).

    Article  CAS  Google Scholar 

  9. McCann, U. D., Szabo, Z., Scheffel, U., Dannals, R. F. & Ricaurte, G. A. Lancet 352, 1433–1437 (1998).

    Article  CAS  Google Scholar 

  10. Allen, R. P., McCann, U. D. & Ricaurte, G. A. Sleep 16, 560–564 (1993).

    Article  CAS  Google Scholar 

  11. Montoya, A. G., Sorrentino, R., Lukas, S. E. & Price, B. H. Harv. Rev. Psychiatry 10, 212–220 (2002).

    Article  Google Scholar 

  12. Morgan, M. J. Psychopharmacology 152, 230–248 (2000).

    Article  CAS  Google Scholar 

  13. Vollenweider, F. X., Gamma, A., Liechti, M. & Huber, T. Neuropsychopharmacology 19, 241–251 (1998).

    Article  CAS  Google Scholar 

  14. McCann, U. D. & Ricaurte, G. A. Neuropsychopharmacology 24, 333–336 (2001).

    Article  CAS  Google Scholar 

  15. Ricaurte, G. A., Yuan, J., Hatzidimitriou, G., Cord, B. J. & McCann, U. D. Science 297, 2260–2263 (2002).

    Article  ADS  CAS  Google Scholar 

  16. Ricaurte, G. A., Yuan, J., Hatzidimitriou, G., Cord, B. J. & McCann, U. D. Science 301, 1479 (2003).

    Article  CAS  Google Scholar 

  17. Grob, C. S., Poland, R. E., Chang, L. & Ernst, T. Behav. Brain Res. 73, 103–107 (1996).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Check, E. The ups and downs of ecstasy. Nature 429, 126–128 (2004). https://doi.org/10.1038/429126a

Download citation

  • Issue date:

  • DOI: https://doi.org/10.1038/429126a

This article is cited by

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing