Intermediate compounds are often produced during a chemical reaction, but they are too short-lived to be easily observed. It seems that a molecular pyramid can persuade them to stick around for a little longer.
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Rebek, J. Molecules in quarantine. Nature 444, 557 (2006). https://doi.org/10.1038/444557a
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DOI: https://doi.org/10.1038/444557a