Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

Immunology

Memory cells sound the alarm

Subjects

In a finding that could have implications for vaccine design, memory immune cells at mucosal surfaces have been shown to respond to encounters with pathogens by issuing signals that recruit other memory cells to the site.

This is a preview of subscription content, access via your institution

Relevant articles

Open Access articles citing this article.

Access options

Buy this article

USD 39.95

Prices may be subject to local taxes which are calculated during checkout

Figure 1: Cytokine alarms accelerate memory T-cell recruitment.

References

  1. Schenkel, J. M., Fraser, K. A., Vezys, V. & Masopust, D. Nature Immunol. 14, 509–513 (2013).

    Article  CAS  Google Scholar 

  2. Virgin, H. W. in Fields' Virology Vol. 1 (eds Fields, B. N., Knipe, D. M. & Howley, P. M.) 335–336 (Wolters Kluwer/Lippincott Williams & Wilkins, 2007).

    Google Scholar 

  3. Flint, S. J., Enquist, L. W., Racaniello, V. R. & Skalka, A. M. Principles of Virology 3rd edn (ASM Press, 2009).

    Google Scholar 

  4. Gebhardt, T. & Mackay, L. K. Front. Immunol. 3, 340 (2012).

    Article  Google Scholar 

  5. Jameson, S. C. & Masopust, D. Immunity 31, 859–871 (2009).

    Article  CAS  Google Scholar 

  6. Shin, H. & Iwasaki, A. Nature 491, 463–467 (2012).

    Article  CAS  ADS  Google Scholar 

  7. Jiang, X. et al. Nature 483, 227–231 (2012).

    Article  CAS  ADS  Google Scholar 

  8. Remakus, S. et al. Cell Host Microbe (in the press).

  9. Xu, R. H., Fang, M., Klein-Szanto, A. & Sigal, L. J. Proc. Natl Acad. Sci. USA 104, 10992–10997 (2007).

    Article  CAS  ADS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Luis J. Sigal.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Smith-Garvin, J., Sigal, L. Memory cells sound the alarm. Nature 497, 194–196 (2013). https://doi.org/10.1038/497194b

Download citation

  • Published:

  • Issue date:

  • DOI: https://doi.org/10.1038/497194b

This article is cited by

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing