C. Glenn Begley explains how to recognize the preclinical papers in which the data won't stand up.
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References
Prinz, F., Schlange, T. & Asadullah, K. Nature Rev. Drug Discov. 10, 712 (2011).
Begley, C. G. & Ellis, L. M. Nature 483, 531–533 (2012).
Rossner, M. 'How to Guard Against Image Fraud' The Scientist (1 March 2006); available at http://go.nature.com/bjjbe4
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C.G.B. is on the board of directors of Oxford Biotherapeutics and on the scientific advisory board of several companies. He holds stock in Amgen.
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Begley, C. Six red flags for suspect work. Nature 497, 433–434 (2013). https://doi.org/10.1038/497433a
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DOI: https://doi.org/10.1038/497433a
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Nitin Gandhi
Now that the six red flags are out – researchers will "take care" of these while "writing" a paper!